Purity Diuretic Medication Mannitol CAS 87-78-5
Synonyms: DL-Mannitol; AI3-19511; Hexahydroxyhexane; Mannidex 16700; NSC 9256; D-Mannitol; D-(-)-Mannitol; hexitol; L-altritol
Molecular Weight :182.1718
CAS Registry Number:87-78-5;69-65-8
Boiling point:494.9°C at 760 mmHg
Vapour Pressur:7.22E-12mmHg at 25°C
annitol is used clinically in osmotherapy to reduce acutely raised intracranial pressure until more definitive treatment can be applied, e.g., after head trauma. It is also used to treat patients with oliguric renal failure. Mannitol can also be used as a facilitating agent for the transportation of pharmaceuticals directly into the brain.
Mannitol is commonly used in the circuit prime of a heart lung machine during cardiopulmonary bypass. The presence of mannitol preserves renal function during the times of low blood flow and pressure, while the patient is on bypass.
Mannitol can also be used to temporarily encapsulate a sharp object (such as a helix on a lead for an artificial pacemaker) while it is passed through the venous system.
Mannitol may be administered in cases of severe Ciguatera poisoning. Severe ciguatoxin, or "tropical fish poisoning" can produce stroke-like symptoms.
Mannitol is the primary ingredient of Mannitol Salt Agar, a bacterial growth medium, and is used in others.
Mannitol increases blood glucose to a lesser extent than sucrose (thus having a relatively low glycemic index) and is therefore used as a sweetener for people with diabetes, and in chewing gums. Although mannitol has a higher heat of solution than most sugar alcohols, its comparatively low solubility reduces the cooling effect usually found in mint candies and gums.
Mannitol can be used to form a complex with boric acid. This increases the acid strength of the boric acid, permitting better precision in volumetric analysis of this acid.
Mannitol is sometimes used as an adulterant or cutting agent for methamphetamines, or other illicit drugs. In popular culture, when it is used in this manner, it is often referred to as baby laxative
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