Naphazoline hydrochloride

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Naphazoline hydrochloride
Synonyms: naphconforte;naphthasoliumchloride;niazol;privinehydrochloride;prizolehydrochloride;
CAS: 550-99-2 MF: C14H15ClN2
MW: 246.74 EINECS: 208-989-2
mp 254-260 °C Water Solubility 170 g/L (20 ºC)
Sensitive Hygroscopic Merck 14,6368
BRN 3716843
Chemical Properties white crystalline powder
Usage adrenergic blocker
Usage antihistamine
Product Categories: Adrenoceptor;NORMODYNE;Pharmaceutical intermediates

Product description

Naphazoline (in the hydrochloride form) is the common name for 2-(1-naphthylmethyl)-2-imidazoline hydrochloride. It is a sympathomimetic agent with marked alpha adrenergic activity. It is a vasoconstrictor with a rapid action in reducing swelling when applied to mucous membrane. It acts on alpha-receptors in the arterioles of the conjunctiva to produce constriction, resulting in decreased congestion. It is an active ingredient in several over-the-counter formulations including Clear Eyes and Naphcon eye drops.


Clinically it is used for the treatment of colds, acute and chronic rhinitis, allergic conjunctivitis, allergic and inflammatory nasal congestion embolism. Local long-term use can lead to blood flow reduction in medication area, which causes resistance decreasing , and results in superinfection. It can not be taken orally. Dropping excess liquid or high concentrations can cause poisoning.

Care should be taken, especially in children. Infants, hypertension, hyperthyroidism patients should take with caution, atrophic rhinitis patients are banned. The interval time of dropping , is preferably not less than 4 to 6 hours.

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Tai'an City Jia biotechnology industry Co.,Ltd


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About Company

Tai'an City Jia Ye biotechnology industry Co.,Ltd is a comprehensive and high-tech enterprise specialize in Steroids Raw materials, chemical synthetic drug, pharmaceutical intermediates, chemical antisepsis, flavor & essence, and food additive, integrating R & D, manufacturing, operating and marketing into an organic whole. Our factory covers an area of 33500 square meters, with clean environment and nice layout. There are several large-sized, medium-sized workshops and QA and research center with advanced equipments.Our products reach the advanced standard of domestic market, many of which reach the international standard, pass Kocher certificate and ISO9001.Our Staff will pursue high quality and perfect brand with untiring efforts, and inherit company spirit on "energy-saving, factual, enterprising, innovative", follow the company management theory of "lives, services or soul of quality", with the first- class products and high-quality service to meet market's demands.. view more »

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